We read with interest the article by Marie Lund and colleagues published in The Lancet Oncology investigating the association between aromatase inhibitor treatment (AIT) and ischaemic cardiotoxicity ...

bDepartment of Clinical Pharmacology, Copenhagen University Hospital—Bispebjerg and Frederiksberg, Copenhagen, Denmark cDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, ...

The grand challenge in structure-based drug design is achieving accurate prediction of binding free energies. Molecular dynamics (MD) simulations enable modeling of conformational changes critical to ...

Key Takeaways Spironolactone is effective for both premenopausal and postmenopausal women Finasteride is primarily used for ...

The team believes that the structure was in use until the 8th century BCE, the middle of the period when the Kings of Judah ruled. A scarab seal from the 8th century BCE uncovered during the ...

Discover the role of phytoestrogens, including soy, in menopause management and breast cancer prevention. Learn how these ...

such as tamoxifen or aromatase inhibitors for breast cancer or androgen ablation for prostate cancer. The effects of chemotherapy-associated cardiovascular toxicity and alterations in ...

Both may be used because testosterone therapy can increase the amount of estrogen in the body due to an increase in aromatase activity. Aromatase is an enzyme that converts testosterone to estradiol, ...

Ion channels are the main regulators of cellular functions, conducting ions selectively through a pore-forming structure located in the plasma membrane, protein–protein interactions one of their main ...

Earth's inner core may actually have two distinct layers. (alexlmx/Canva Pro) "We found evidence that may indicate a change in the structure of iron, which suggests perhaps two separate cooling events ...

Mission Statement: Evidence-based Complementary and Alternative Medicine (eCAM) is an international, peer-reviewed journal that seeks to understand the sources and to encourage rigorous research ...