Dynamic landscape of peripheral blood immunity during human pregnancy FAYETTEVILLE, GA, UNITED STATES, April 16, 2025 /EINPresswire / -- Th ...

To gain insight into its role in arthritis and given that NAMPT is identified as a novel mediator of innate immunity, we addressed the function of monocyte-derived NAMPT in experimental arthritis by ...

在细胞实验中，培养了小鼠树突状细胞系 DC2.4、小鼠骨髓来源的树突状细胞（Bone Marrow - Derived Dendritic Cells，BMDCs）以及人单核细胞来源的树突状细胞（Monocyte - Derived Dendritic Cells，moDCs）。同时，运用了转录组分析技术，全面检测细胞基因表达的变化；利用染色质 ...

Here we show that SARS-CoV-2 mRNA vaccination significantly establishes histone H3 lysine 27 acetylation (H3K27ac) at promoters of human monocyte-derived macrophages, suggesting epigenetic memory.

Life or death of individual cells determines health and disease in multi-celled organisms. Cell death is crucial for organogenesis in utero and successful control of host cell populations in ...

End-stage renal disease (ESRD) patients experience immune compromise characterized by complex alterations of both innate and adaptive immunity, and results in higher susceptibility to infection and ...

These oncoproteins are an attractive target for a therapeutic cancer vaccine. Conclusions: These findings strongly suggest that in pre-clinical studies, DNA vaccination with ITI-3000, using the UNITE™ ...

Amino acids (AAs) are necessary nutrients which act not only as building blocks in protein synthesis but also in crucial anabolic cellular signaling pathways. It has been demonstrated that SLC7A5 is a ...