雷帕霉素（mTOR）途径在调节T细胞分化和生长中起关键作用，并参与HIV-1复制的多个步骤。研究表明，mTOR在特定T细胞中的激活促进了HIV-1的复制，而mTOR抑制剂则能减少病毒生长。

1Department of Pediatric Hematology and Oncology, Justus-Liebig University, Giessen, Germany. 2Department of Pathology, Boston Children´s Hospital, Boston, Massachusetts. 3Department of Pediatric ...

为探究外周免疫系统在阿尔茨海默病（AD）发病中的作用机制，研究人员开展相关研究。结果发现其通过多种途径影响 AD 进程。该研究为 AD 治疗提供新靶点，对开发新疗法意义重大，推荐科研读者阅读。

Experimental autoimmune encephalomyelitis (EAE) is a model of the neuroimmune system responding to priming with central nervous system (CNS)-restricted antigens. It is an excellent model of post ...

There is increasing evidence to support a role of T cells—CD4+, CD8+, and NK cells, as well as APCs. Early immune vascular changes are a prominent feature shared by skin and joints with apparent ...