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Warner Bros. Games is making big cuts, closing three studios — Monolith Productions, Player First Games, and WB Games San Diego — and canceling its long-in-development Wonder Woman game ...

Monolith Productions, Player First Games, and WB San Diego have been shut down. The open world Wonder Woman video game has been canceled and three of Warner Bros. Games' studios have been shut down.

“We have had to make some very difficult decisions to structure our development studios and investments around building the best games possible with our key franchises -– Harry Potter, Mortal ...

The news of studio closures at WB Games comes via a report from Bloomberg’s Jason Schreier. The report was quickly confirmed by a statement from Warner Bros. Games to Kotaku. We have had to make ...

TL;DR: Warner Bros Games is closing Monolith Productions, known for the Middle-earth series, and cancelling the Wonder Woman game. Warner Bros Games is shutting down Monolith Productions, the ...

However, Warner Bros. had other plans. After the runaway success of Shadow of Mordor, WB started mobilizing to patent the Nemesis system so no one else could use it in 2015 then proceeded to only ...

SOUTHFIELD, Mich. (WXYZ) — Temporary closures are already beginning for the massive I-696 project in Oakland County. As the Michigan Department of Transportation ...

CDK4/6 抑制剂耐药的机制多种多样，包括 Rb 基因缺失或表达下调、细胞周期蛋白 cyclin E 过表达、CDK2 激活、CDK6 过表达、PTEN 缺失导致 PI3K/AKT/mTOR 通路 ...

为解决BCR::ABL1阳性白血病中CDK6高表达导致的代谢重编程及耐药问题，研究人员开展了一项关于CDK6在白血病细胞代谢调控中的作用机制研究。他们发现CDK6激酶活性对氧化磷酸化（OXPHOS）的调控至关重要，并揭示了其与NRF-1的竞争关系。研究表明，联合使用CDK4/6 ...