Scientists are exploring gene editing as a way to correct trisomy at the cellular level. Using CRISPR-Cas9, researchers successfully removed extra copies of chromosome 21 in Down syndrome cell lines, ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...

CRISPR-Cas9 is a precision genome editing technology that can knock out, activate or fine-tune the expression of individual genes. We provide access to CRISPR KO (knockout), CRISPRi (interference ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

By using clustered regulatory interspaced palindromic repeats (CRISPR)-CRISPR-associated protein (Cas9) knock-out screens, they systematically deleted each gene to see if its absence allowed tumors to ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...

2024 — Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the ...

Both gene knockout and knock-in models are powerful ... regularly interspaced short palindromic repeats (CRISPR)/associated ...

CRISPR/Cas9, a groundbreaking gene-editing technology, holds the potential to transform oilseed production in Kashmir ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...