本研究通过CRISPR/Cas9技术敲除GLS1基因，发现在多种肿瘤细胞系中，GLS1缺失均导致细胞增殖显著受阻。补充谷氨酸或同时补充GLS1的两种剪接变体（GAC和KGA）能够完全恢复细胞增殖能力。进一步通过代谢物回补实验、代谢质谱、代谢组学及同位 ...

New research uncovers that aging activates a new type of stem cell that rapidly produces fat cells, explaining why belly fat often expands in middle age.

According to a new study published in BMC Cancer, “CBD demonstrated significant anticancer effects, including induction of ...

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, ...

Gilead Sciences, Inc. ( NASDAQ: GILD) Q1 2025 Earnings Conference Call April 24, 2025 4:30 PM ET Jacquie Ross - SVP, Treasury & IR Daniel O'Day - Chairman, CEO Johanna Mercier - Chief Commercial ...

The following is a summary of "ADORA2B promotes proliferation and migration in head and neck squamous cell carcinoma and is ...

Many different cancer treatments work to directly target the tumor or the cells around it. The immediate goal is to mitigate ...

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ ...

Even with prevention measures and timely, aggressive intervention, tumor lysis syndrome (TLS) remains life-threatening, as a case study in small cell lung cancer (SCLC) illustrates.

Emerging research highlights how vitamin D boosts immunity and reduces colorectal cancer (CRC) risk by regulating ...

Cancer patients invariably develop resistance to targeted drugs, so drugmakers develop strategies to combat it before ...