Analysis of data from 537 US hospitals reveals that ceftolozane-tazobactam and ceftazidime-avibactam are the most frequently ...

为解决细菌异质性耐药（HR）机制及检测难题，柏林自由大学的研究人员对阴沟肠杆菌复合菌株展开研究。结果发现质粒上基因复制 - 扩增（GDA）导致对头孢他啶的 HR。该研究对理解 HR 机制和临床治疗意义重大，推荐科研读者阅读。

为解决发展中国家手术部位感染（SSIs）相关数据匮乏问题，埃塞俄比亚 Arba Minch General Hospital 研究人员研究 SSIs 流行、微生物谱及相关因素。发现 SSIs 患病率高且耐药严重，该研究对防控感染、合理用药意义重大，值得科研读者一读。

Review of data from the trial found that the vaccine was not sufficiently effective at preventing invasive E coli disease ...

in 0.45% sodium chloride injection SP 0.4 mL/min Ceftazidime Glaxo Wellcome 6039T86 2 g (80 mg/mL) in 0.45% sodium chloride injection SP 0.9 mL/min Ceftriaxone Roche 3829 2 g (66.7 mg/mL ...

NHSO approves six new drugs for insurance, enhancing treatments for tuberculosis, hepatitis C, and lymphoma, saving millions ...

Bacterial insertion sequences (IS) are small DNA segments (<2.5 kb) with a simple genetic organization. Most IS elements exhibit short terminal inverted repeat sequences (IR) and encode a transposase, ...

Doses and/or dosing intervals varied significantly for 12 antibiotics (amikacin, gentamicin, netilmicin, tobramycin, vancomycin administered as continuous infusion, ceftazidime, cloxacillin, oxacillin ...

Three of these six pathogens are antibiotic-resistant Gram-negative bacteria. Recently, antibacterial drugs against ESBL-producing Gram-negative bacteria accounted for ∼15% (2 out of 13) of all ...

编者按：多重耐药铜绿假单胞菌（MDR-PA）是一种对至少三种不同类别的抗菌药物（如β-内酰胺类、氨基糖苷类、喹诺酮类等）耐药的菌株，主要在医院环境中传播，常见于免疫功能低下或长期住院的患者。近年来，新型抗菌药物头孢他啶/阿维巴坦（CZA）和头孢洛扎/ ...