The study by Pudlowski et al. shows that a previously-identified protein complex, composed of delta- and epsilon-tubulin together with TEDC1 and TEDC2, functions in generating centriolar triplet ...

Among these, the torus critically establishes the characteristic orthogonal engagement. We also demonstrate that engagement mediated by the cartwheel and torus is progressively released during ...

Oocyte maturation is a complex and dynamic process regulated by the coordination of ovarian cells and numerous extraovarian signals. From mammal studies, it is learnt that lipid metabolism provides ...

compound microtubules may also be involved in recruiting or regulating enzymes that modify centrioles during their maturation. During the first cell cycle after their formation, procentrioles acquire ...

In S phase, this link weakens further and is proceeded by pro-centriole formation (i.e., new daughter centriole biogenesis). In G2, centrosome separation occurs and each new centrosome begins ...