The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

Centromeres are specific sites on chromosomes that are essential for mitosis and genome fidelity. This valuable research advance builds upon previous studies to convincingly show that the ...

英文名称：Histone H2A (1 - 20) 中文名称：组蛋白 H2A（1 - 20）片段 氨基酸序列：由组蛋白 H2A 的前 20 个氨基酸组成，序列为：Met - Arg - Gly - Ala - Lys - Glu - Lys - Ser - Lys - Gln - Lys - Asn - Ala - Val - Lys - Ala - Ala - Ser - Ser - Lys ...

virginiana and F. chiloensis. However, the differences in centromere characteristics and evolutionary patterns between wild and cultivated octoploids have remained poorly understood. In a study ...

virginiana and F. chiloensis. However, the differences in centromere characteristics and evolutionary patterns between wild and cultivated octoploids have remained poorly understood. In a study ...

"These findings suggest that histone modifications in macrophages not only activate genes involved in the immune response, but that these genes additionally form guanine quadruplex DNA structures ...

How precisely mRNA vaccines train innate immune cells to shape protective host defense mechanisms remains unknown. Here we show that SARS-CoV-2 mRNA vaccination significantly establishes histone H3 ...

How chromosomes shape up for cell division Scientists have shown how overlapping loops of DNA stack upon each other in dividing cells to give rise to rod-shaped chromosomes Date: March 24, 2025 ...

Scientists at EMBL have captured how human chromosomes fold into their signature rod shape during cell division, using a groundbreaking method called LoopTrace. By observing overlapping DNA loops ...

The fusion protein binds to the LacO domains (1), and incorporates the specialized centromeric histone CENP-A into and along neighboring chromatin (2). In turn, the region of CENP-A-containing ...