近年来，随着对肿瘤生物学特性的深入认识，特别是肿瘤干细胞的发现以及免疫治疗的突破性进展，肿瘤领域迎来了前所未有的变革。在这一背景下，抑制剂和人源化单抗在肿瘤干细胞与免疫研究中的应用日益受到关注，并展现出巨大的潜力。AbMole多年来持续关注小分子抑制 ...

当全球每年新增4.1万例骨肉瘤患者的警报持续拉响，青少年骨肿瘤治疗领域正面临着前所未有的挑战。传统化疗带来的严重副作用使60%患者出现不可逆器官损伤，而免疫检查点抑制剂在冷肿瘤中的响应率不足15%。在这双重困境下，浙江大学医学院附属嘉兴医院团队在《Chemical Engineering Journal》发表的突破性研究，为这场抗癌持久战带来了破局曙光。

This important study shows that the Nora virus, a natural Drosophila pathogen that also persistently infects many laboratory fly stocks, infects intestinal stem cells (ISCs), leading to a shorter life ...

Immunostimulatory assays suggest condensate-specific activation of the IRF pathway via cGAS-STING signaling. This study provides a framework for developing biomolecular condensates with customizable ...

The upregulation of the pro-survival pathway in senescent cells inhibits the formation of apoptotic pores, resulting in the release of miMOMP, sublethal apoptosis and mtDNA into cytoplasm, and mtDNA ...

For many caught up in sting operations like the one that ensnared Denton, they say, the victim is purely theoretical. Bonnie Burkhardt, an expert witness and the author of Manufacturing Criminals ...

Copyright 2025 The Associated Press. All Rights Reserved. Copyright 2025 The Associated Press. All Rights Reserved. The nameplate stands empty on the desk that ...

Bloomington police said Eichorn was among 14 men arrested in a prostitution sting this month. Officers say Eichorn was texting with an undercover officer posing as a 17-year-old girl. In the text ...

STRATFORD — A sting meant to curb prostitution at area motels resulted in the arrest of 15 men over the last several weeks, police said Wednesday. The continuing operation followed the ...

Forbes contributors publish independent expert analyses and insights. Hugh McIntyre covers music, with a focus on the global charts.

The wife of Minnesota state senator Justin Eichorn has filed for divorce after his arrest in an underage sex sting — and on the same day he was hit with extra charges. Brittany Eichorn ...