资讯

American Association of Individual Investors2 天
Why Lam Research Corporation’s (LRCX) Stock Is Up 5.33%
Lam Research Corporation’s LRCX share price has surged by 5.33%, which has investors questioning if this is right time to ...
EMBO Press1 天
Molecular insights into the effect of 1,6-hexanediol on FUS phase separation
Alkanediols such as 1,6-hexanediol disrupt many phase-separated condensates in cellula and in vitro, but how molecular interactions are perturbed by these compounds remains unclear. This study uses ...
Gut2 天
DNAJ-PKAc fusion heightens PLK1 inhibitor sensitivity in fibrolamellar carcinoma
Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ-PKAc fusion oncoprotein. However, the underlying mechanism of DNAJ-PKAc’s ...
eLife4 天
DuoHexaBody-CD37 induces direct cytotoxic signaling in diffuse large B-cell lymphoma
This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...