We propose that targeting the metabolic defects in this pathway might provide an opportunity for the development of kidney cancer gene-specific therapies that are more durable and more effective ...

could lead to the development ... Scientists have examined the gene expression patterns of single cells from 5 human fetal kidneys to create the most complete atlas of the fetal kidney to date.

The kidney is a major site of organ damage caused by drug toxicity. This frequently manifests during drug development and/or in standard clinical care. Nephrotoxicity resulting from drug exposure ...

The team indicates that different genetic predispositions give rise to different tumor development pathways and kidney structures, and have identified those that restrict the growth of tumors.

“We believe this work can form a foundation for the development of neoantigen vaccines in kidney cancer,” said Braun.

Kuure lab studies mechanisms of organogenesis with the focus on embryonic kidney and in vivo modeling of rare diseases. Congenital renal malformations are among the most common birth defects and arise ...

Chronic kidney disease, uric acid issues are on a surge. With increasing sedentary lifestyle, kidneys get affected in ways that we not even understand. Uric acid levels have an essential ...

“This new indication will not only allow us to reduce the risk of progression of CKD, or development of end-stage kidney disease in adults with CKD and type 2 diabetes, but will also aid in ...