could lead to the development ... Scientists have examined the gene expression patterns of single cells from 5 human fetal kidneys to create the most complete atlas of the fetal kidney to date.

We propose that targeting the metabolic defects in this pathway might provide an opportunity for the development of kidney cancer gene-specific therapies that are more durable and more effective ...

The methods to achieve this goal are severalfold and include increasing the number of live kidney donors, increasing deceased donation, and preventing the development of renal failure in the first ...

The team indicates that different genetic predispositions give rise to different tumor development pathways and kidney structures, and have identified those that restrict the growth of tumors.

“We believe this work can form a foundation for the development of neoantigen vaccines in kidney cancer,” said Braun.

Kuure lab studies mechanisms of organogenesis with the focus on embryonic kidney and in vivo modeling of rare diseases. Congenital renal malformations are among the most common birth defects and arise ...

The chronic kidney disease drug development landscape is evolving at an unprecedented pace, driven by breakthrough approvals, billion-dollar mergers and acquisitions, and increasing regulatory support ...