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PepH3 修饰纳米载体:跨越血脑屏障递送疗法的新希望
血脑屏障(BBB)限制药物进入大脑,影响脑部疾病治疗。研究人员开展 PepH3 修饰纳米载体跨越 BBB 递送治疗药物的研究,发现 PepH3 增强纳米颗粒摄取和单域抗体(sdAb)跨 BBB 转运。这为脑部疾病药物递送提供新策略,有望改善治疗效果。
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