SAST and syntrophin were highly associated with purified microtubules and microtubule-associated proteins, whereas utrophin and dystrophin were only partially associated with microtubules.
ZJU-Hangzhou Global Scientific and Technological Innovation Canter, Zhejiang University, Hangzhou, Zhejiang 311215, China College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, ...
An inherited disorder affecting primarily boys, DMD is characterized by the progressive loss of skeletal, heart and lung muscle. It is caused by a mutation in the gene for the dystrophin protein, ...
Muscular dystrophy is caused by a lack of certain proteins that are needed for muscle structure and function. Specifically, many of the types of MD are caused by a lack of a protein called dystrophin, ...
FITC-Drisapersen是一种通过化学键合将荧光染料异硫氰酸荧光素(FITC)与Drisapersen分子相结合的标记化合物。Drisapersen 是一种反义寡核苷酸,在 dystrophin pre-mRNA 剪接过程中诱导 51 号外显子跳跃,合成部分功能性 dystrophin。而FITC的引入则赋予了该化合物强烈的绿色 ...
Lymphocyte subset enumeration was performed by flowcytometry. 50µl of whole blood were mixed with anti-CD16 (clone 3G8, BD Pharmingen), -CD45-PerCP (clone 2D1, BD Biosciences), -CD19-PE-Cy7 (clone ...
Although heterogeneity is recognized within the murine satellite cell pool, a comprehensive understanding of distinct subpopulations and their functional relevance in human satellite cells is lacking.
The samples were incubated overnight at 4°C followed by washing with 1 × PBS three times before the addition of the FITC labeled secondary antibody. The samples were washed three times with 1 × PBS to ...