(2) The mRNA expression levels of Murf1 and atrogin-1. We confirmed that these muscle atrophy inducing factors did not differ among WT, BMD, and mdx mice. The data is presented in Fig. 4–figure ...

The researchers noted that in DMD, dystrophin mutations not only disrupt the dystrophin protein that is made, the mutant gene that is transcribed (as mRNA) breaks apart into pieces that can then take ...

Identifying expression patterns of miRNAs in COPD may enhance our understanding of the mechanisms of disease. A study was undertaken to determine if miRNAs are differentially expressed in the lungs of ...

In addition, we confirmed the decreased truncated dystrophin levels and the decreased nNOS expression levels in all BMD mice ... cDNA was synthesized using the QuantiTect Reverse Transcription Kit ...

Dr. Vinod Balachandran says mRNA vaccines could stimulate the immune system to recognize and attack pancreatic cancer cells. An experimental approach to treating pancreatic cancer with the messenger ...

Gerry Baker is Editor at Large of The Wall Street Journal. His weekly column for the editorial page, “Free Expression,” appears in The Wall Street Journal each Tuesday. Mr. Baker is also host ...

CureVac and partner GSK are, meanwhile, also developing an mRNA-based flu vaccine, but are a little further back in development, as their shot is in phase 1 testing.

The trial compared Moderna's MRNA-4157/V940 vaccine given alongside Merck & Co's cancer immunotherapy Keytruda (pembrolizumab) to Keytruda alone in patients with the skin cancer melanoma.