Duchenne muscular dystrophy (DMD) is a rare hereditary disease that is associated with progressive muscle wasting. The ...

Utrophin increase in muscle cells after transcriptional adaptation normalises cell function in Duchenne muscular ...

Utrophin increase in muscle cells after transcriptional adaptation normalises cell function in Duchenne muscular dystrophy ...

(2) The mRNA expression levels of Murf1 and atrogin-1. We confirmed that these muscle atrophy inducing factors did not differ among WT, BMD, and mdx mice. The data is presented in Fig. 4–figure ...

The researchers noted that in DMD, dystrophin mutations not only disrupt the dystrophin protein that is made, the mutant gene that is transcribed (as mRNA) breaks apart into pieces that can then take ...

Additionally, mRNA expression lasted up to four weeks—significantly longer than the typical five-day expression period of LNPs. Notably, the polymer ensured mRNA expression only at the injection ...

Identifying expression patterns of miRNAs in COPD may enhance our understanding of the mechanisms of disease. A study was undertaken to determine if miRNAs are differentially expressed in the lungs of ...