Gut Microbiota in Immuno-Oncology: A Practical Guide for Medical Oncologists With a Focus on Antibiotics Stewardship Bispecific antibodies (bsAbs) have emerged as a novel class of therapeutics, ...

Lysosomes are subcellular organelles that are mainly responsible for degradation of proteins internalized by cells by endocytosis and ... During the endosome–lysosome transition, the ...

Division of Cardiology, Department of Medicine, University of California, Los Angeles (H.M.S., K.E.J., T.Q.d.A.V., E.J.T.). Division of Cardiology, Department of ...

"Cells have two important 'junk compartments': the lysosome and the proteasome," Silverman said. "They collect junk and other components that are not useful to the cell, chew them up and get rid ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Toll-like receptor 4 (TLR4) signaling at the ...

"Cells have two important 'junk compartments': the lysosome and the proteasome," Silverman said. "They collect junk and other components that are not useful to the cell, chew them up and get rid ...

"Cells have two important 'junk compartments': the lysosome and the proteasome," Silverman said. "They collect junk and other components that are not useful to the cell, chew them up and get rid ...

Fcα/μR also mediated primary B lymphocyte endocytosis of IgM-coated Staphylococcus aureus. Thus, Fcα/μR is involved in the primary stages of the immune response to microbes. Figure 3 ...

We are riddled with microplastics. It is in our bloodstream, in our lungs, in our liver – pretty much anywhere you look in the human body, you will find minuscule bits of plastic. And there are ...

Hence, pharmacological upregulating lysosome machinery via targeting TFEB represents a promising approach to treat NPC and related lysosomal storage diseases, and provides the possibility of TFEB ...

The distal portions of the nephron, including the distal convoluted tubule (DCT), the connecting tubule (CNT), and the cortical collecting duct (CCD), are essential to fine-tune the excretion of ...