Epigenetic alterations have emerged as critical factors in the pathogenesis of brain cancer, particularly gliomas. This article explores the impact of organochlorine pesticides (OCPs) on the ...

Research reveals that DNA mutations may influence epigenetic clocks, raising new questions about the aging process.

A new study draws a line between random genetic mutations and predictable epigenetic changes used to measure biological aging ...

Disrupting any of the three systems that contribute to epigenetic alterations can cause abnormal activation or silencing of genes. Such disruptions have been associated with cancer, syndromes ...

However, it is still controversial whether IM itself is precancerous or paracancerous. Here, we aimed to explore the precancerous nature of IM by analysing epigenetic alterations. Design Genome-wide ...

Epigenetic mechanisms in general, and chromatin alterations in particular, are involved in all aspects of cancer development and progression. A number of elegantly conducted translational studies have ...

Modulation of a single molecular factor is unlikely to be sufficient to attenuate or reverse the progression of stroke pathology. Epigenetic alterations such as DNA methylation, histone modifications, ...

A new study suggests that diets high in fast food, processed red meat, and soda but low in fruits and vegetables may be ...

Despite their differences, both mechanisms contribute to molecular aging. Researchers have long speculated about a potential connection between genetic mutations and epigenetic alterations. The new ...

Recent research has provided strong evidence suggesting that a variety of epigenetic mechanisms may underlie transgenerational inheritance. These include differential DNA methylation, histone ...