It has been found that ineffective erythropoiesis in β-thalassemia is closely associated with a high accumulation of Reactive oxygen species, a product of oxidative stress, in erythroid cells. During ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

After centrifugation at 300 g, 4°C for 5 min, the cell pellet was resuspended in RPMI 1640/10% fetal bovine serum (FBS; GIBCO). After lysing the red blood cells with Red Blood Cell Lysis Solution ...

Jan. 23, 2025 — There's a downside to being a powerful alpha male -- at least if you're a baboon. Studies show that despite their high rank, the No. 1 males in baboon society are also some of ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Bone-marrow-derived multipotent progenitor stromal cells — or mesenchymal stem cells (MSCs) — are the common predecessors of cells of the mesenchymal lineage, such as bone, cartilage and fat ...

Acanthocyte Erythrocyte identified by numerous spiny cytoplasmic projections; similar to a Burr cell Acanthocytosis, condition in which the majority of erythrocytes are acanthocytes. Anemia ...

A recently study published in Nutrients reports that the regular consumption of mangoes may improve inflammation, insulin ...

The cellular enzyme is overexpressed in up to 90% of cancers, but is almost always absent in normal cells, with a few exceptions ... to be Bristol-Myers Squibb's erythroid maturation agent ...