G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

This family is now known as G-protein-coupled receptors, and the studies by Lefkowitz and Kobilka have been crucial to understanding how they function. The insights have been ...

Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for ...

EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel ...

Researchers have developed a standardized numbering system for adhesion GPCRs, improving knowledge transfer and disease analysis. This AI-driven system, based on 14,000 modelled structures, ...

Cottage cheese doesn’t get nearly enough love. Harris-Pincus recommends adding it to your routine for an easy dose of protein. With roughly 12 g of protein and 100 calories per ½ cup ...