ROS produced from oxidative phosphorylation (ETC) may cause lipid peroxidation if the activity of mitochondrial GPX4 is compromised. Export of ISC occurs with the help of mitoNEET proteins (mNT). This ...
为解决 TTM 最佳温度及作用机制不明等问题,安徽医科大学研究人员开展 TTM 对 PRMD 影响的研究,发现 33°C 的 TTM 可减轻 PRMD,与激活 Nrf2、调节铁稳态有关。该研究为心脏骤停治疗提供新思路,值得科研读者一读。
2012). In 2018, the Nomenclature Committee on Cell Death (NCCD) defined ferroptosis as “a form of regulatory cell death initiated by oxidative perturbations of the intracellular microenvironment that ...
开罗大学医学院医学生理学系的 Hanan Seddiek、Mira Hanna 等研究人员在Scientific Reports期刊上发表了题为 “Deferiprone ameliorates cisplatin-induced peripheral neurotoxicity via ferritinophagy adjustment ... 定量实时 PCR 分析细胞抗氧化相关基因(GPX4 ...
Objective Investigating the effect of ferroptosis in the tumour microenvironment to identify combinatory therapy for liver cancer treatment. Design Glutathione peroxidase 4 (GPx4), which is considered ...
Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China ...
Department of Respiratory and Critical Care Medicine, National Health Commission (NHC) Key Laboratory of Respiratory Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science ...
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