Genetic engineering deployed to insert gene for human insulin into a bacterium, thus harnessing the substance for widespread ...

Single-molecule biophysics is the study of the dynamics and interactions of individual biomolecules to understand how they carry out their functions in living cells. For example, monitoring the ...

The international team describes their results and the underlying molecular mechanism in Cell Metabolism. Ergothioneine is a natural compound found in certain fungi such as oyster or shiitake ...

Microwave-fixation of the brain was employed to enable in situ snapshots of brain glycogen and metabolome as well as the phosphorylation-dependent activation state of GYS1. In conjunction with the ...

A new study by Weill Cornell Medicine and the Boyce Thompson Institute reveals that the body produces a molecule, BA-MCY, which counteracts gut microbes’ signals to regulate bile acid production, ...

Glycogen storage disease (GSD) refers to a group of rare genetic conditions that affect how the body stores and breaks down glycogen. The most common type is type I, also called von Gierke disease ...

In 2018 many of the Department's activities moved into a custom-built facility at Imperial’s new White City Campus. This landmark building has been designed to support our vision for chemistry. It ...

Attempts to design small molecule therapies directed to this cytokine have not led to approved products yet. Here we report the discovery and development of a potent small molecule inhibitor of TNF ...