“3-NPA irreversibly binds to and inhibits succinate dehydrogenase in the mitochondria, thereby blocking the citric acid cycle and ATP generation in cells, which would explain the observed severe ...

By reprogramming glycolysis, disrupting the TCA cycle, and exploiting lipid metabolism, Mtb outcompetes immune responses, sustains its growth, and establishes a persistent niche within the host. The ...

A Nobel Prize, of course. Such was the case for Hans Krebs, the biochemist who nabbed the award in 1953 for discovering the citric acid cycle, or “Krebs cycle”—the cellular pathway that converts ...

Institution of Biorefinery Engineers, Scientists and Technologists, Faculty of Engineering and Physical Sciences. Professor Jhuma Sadhukhan is a global leader in BIOREFINERY DESIGN, PROCESS ...

Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Sichuan Provincial Key Laboratory for Acupuncture & Chronobiology, Key Laboratory of Acupuncture for Senile Disease ...

We also performed mass spectrometry (MS)-based metabolomics in organoids. Estrogens altered the levels of metabolites from various pathways, including aerobic glycolysis, citric acid cycle, urea cycle ...