Previously, we showed that RV enhances mucin gene expression and increases goblet cell number in a COPD mouse model. This study examines whether RV causes sustained GCH in relevant models of COPD.

Methods Nasal (N) and tracheal (T) epithelial cells (EC) were collected from children categorised with atopy and/or wheeze based on specific IgE to locally common aeroallergens and a questionnaire ...

In addition, ACE2 and TMPRSS2 are also coexpressed in both upper epithelial and gland cells from oesophagus and absorptive enterocytes from ileum and colon. How might it impact on clinical practice in ...

Pathogens infecting the porcine respiratory mucosa via aerosols and/or droplets often initiate their replication in respiratory epithelial cells (RECs) in the upper tract (7). After this first ...

cross-talk in the microenvironment of the airway epithelium. Goblet cells are located throughout the conducting airway of the respiratory epithelium. Ultrastructural analysis of these cells shows that ...

Using a combination of single-cell RNA-seq and lineage-tracing, we find that progenitor cells are the principal targets of ageing, whereas the function of individual mature thymic epithelial cells is ...

The follicle stem cells (FSCs) in the Drosophila ovary are an important experimental model for the study of epithelial stem cell biology. Although decades of research support the conclusion that there ...