Tumor-associated macrophages (TAMs) are a phenotypically diverse, highly plastic population of cells in the tumor microenvironment (TME) that have long been known to promote cancer progression. In ...

Diabetic nephropathy (DN) is the most common chronic kidney disease. Accumulation of glucose and metabolites activates resident macrophages in kidneys. Resident macrophages play diverse roles on ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

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kuleuven.be Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the ...

Medically reviewed by Gagandeep Brar, MD Bone marrow is the deep, interior portion of your bone. Your bone marrow, which has ...

23 In a normal immune response, after infection by an intracellular pathogen, macrophages are activated by pattern-recognition receptors, at which point they secrete proinflammatory cytokines and ...

Hemosiderin is a protein compound that helps the body store iron. When trauma or medical issues affect capillaries, blood cells break down and iron is released from hemoglobin in the blood forming ...

During a Case-Based Roundtable® event, Neeraj Agarwal, MD, and participants discussed how they might determine which ...