Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in ...

We spatiotemporally pattern these cues using photoinduced degradation, viscoelasticity, and bond formation to study how intestinal stem cell colonies respond to alterations in geometric confinement, ...

The epithelial lining of our intestine is organized in a crypt-villi architecture and serves many essential functions including maintenance of barrier, digestion and nutrient absorption. Due to the ...

An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures ... and differentiation of intestinal epithelial tissue.

Lab-grown intestinal organoids mimic gut structures, including crypts, which are crucial for gut regeneration as they are home to stem cells. However, the exact mechanical processes driving crypt ...