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TEPEZZA, as the first FDA-approved treatment for thyroid eye disease, marks a major breakthrough in managing TED, addressing a critical medical gap for patients who have long had few treatment ...

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Heterocyclic insulin-like growth factor 1 receptor (IGF-1R; CD221) inhibitors potentially useful for the treatment of thyroid-associated ophthalmopathy (Graves’ ophthalmopathy) have been disclosed in ...

The table below is a review of notable updates that occurred in January 2025 for investigational products in development.

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Weight gain is possible with any insulin product. Soliqua also contains lixisenatide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist. GLP-1 receptor agonists may cause weight loss.

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1 Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China 2 Center for Cancer Research, The University of Hong Kong, Hong Kong, China 3 Department of Surgery, The University of ...

CHO cells stably expressing IGF-1R or insulin receptor (IR) were 'serum-starved' for 2 h, incubated with JB3 for 20 min at 37 °C, then incubated with 100 nM IGF-1 (for CHO.IGF-1R cells ...

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