A multifactorial approach should be used to account for all the factors involved-that is, the internal and external risk factors as well as the inciting event (the injury mechanism). Although such ...

Structural and cellular assays and molecular dynamics simulations reveal the mechanism of action of γ-glutamyl carboxylase, which involves cholesterol and vitamin K. Protein kinase R-like ...

Large, well-controlled clinical studies have established the efficacy and safety of initial adjuvant therapy with letrozole or anastrozole versus the previous standard of 5 years of adjuvant ...

Mission Statement: Evidence-based Complementary and Alternative Medicine (eCAM) is an international, peer-reviewed journal that seeks to understand the sources and to encourage rigorous research ...

This study presents fundamental insights into overcoming resistance in hormone receptor-positive breast cancer by demonstrating that sustained CDK4/6 inhibitor treatment, either alone or in ...

New York-headquartered Stemline, which licensed global rights to elacestrant from Radius Health in July 2020, said the new drug is the first hormonal therapy with a novel mechanism of action in ...