By employing a proprietary linker and conjugation chemistry, we developed an ADC with a TLR7 agonist covalently linked to a mouse IgG2a antibody that targets mouse tyrosinase-related protein 1 (TRP1 ...

Figure 1 TLR signaling pathway in innate immune cells. TLR5, TLR4, and the heterodimers of TLR2–TLR1 or TLR2–TLR6 prefer to recognize the membrane components of pathogens at the cell surface, whereas ...

newcastle.edu.au Background Asthma exacerbations represent a significant disease burden and are commonly caused by rhinovirus (RV), which is sensed by Toll-like receptors (TLR) such as TLR7. Some ...