newcastle.edu.au Background Asthma exacerbations represent a significant disease burden and are commonly caused by rhinovirus (RV), which is sensed by Toll-like receptors (TLR) such as TLR7. Some ...

Type 1 IFN produced by pDCs has beneficial roles in host immunity to viral infections (9, 10), but it is also implicated in the pathogenesis of certain types of autoimmune diseases, including systemic ...

Virus-like particles (VLPs) are used in different marketed vaccines and are able to induce potent antibody responses. The innate pattern recognition receptors TLR7/8 recognize single stranded (ss) RNA ...