Unger was able to nip calcium transients in the bud by injecting a “puff” of sTREM2 into the mouse brain with a pipette; this temporarily silenced nearby neurons, and it did so in wild-type or TREM2 ...

Every year roughly 1,000 Canadians are diagnosed with amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig’s disease). Some 4,000 Canadians are currently living with the disease. There are few ...

There are very few effective treatments to slow the symptoms of amyotrophic lateral sclerosis, also known as motor neurone ...

The body’s wound healing system, which is necessary to stop secondary injuries, involves a highly coordinated response of various cell types. These include astrocytes, which are cells in the central ...

Researchers used preclinical models to uncover Tim-3's role in microglia, the brain's resident immune cells, and have identified it as a promising therapeutic target for Alzheimer's disease.

巨噬细胞亚群多样，功能复杂。其中，小胶质细胞（microglia）作为巨噬细胞家族中的特殊成员，广泛参与中枢免疫监视与炎症反应、神经发育及其退行性疾病等生理病理过程。自 1919 年被发现至今的一百多年里，小胶质细胞一直被认为是中枢神经系统（CNS ...

SHENZHEN -- Chinese scientists have, for the first time, confirmed the existence of microglia in the peripheral nervous system (PNS). This breakthrough provides novel insights into PNS development ...

In a study published in Cell on April 7, a research team led by Prof. LI Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presence ...

including disease-associated microglia and B cells. More data are needed on its efficacy and safety in treating relapsing multiple sclerosis. In two phase 3, double-blind, double-dummy ...

Get Instant Summarized Text (Gist) Digital technology use in children aged four to six is linked to poorer well-being, including social, emotional, and behavioral difficulties. The analysis, based ...