An international team of researchers co-led by Job Dekker, Ph.D., at UMass Chan Medical School, have identified rules that ...

In this cross-journal Collection, we invite submissions on topics broadly covering the regulation and mechanisms of mitosis, mitotic defects, surveillance mechanisms in the ensuing interphase and ...

Overexpression of HDAC6 in mice results in a significant thickening of the corneal epithelium. Mechanistic studies reveal that HDAC6 overexpression disrupts mitotic spindle orientation and positioning ...

The authors provide an interesting observation that ER-targeted excess misfolded proteins localize to the nucleus within membrane-entrapped vesicles for further quality control during cell division.

Taken together, ER-FlucDM-mCherry aggregates in the nucleus have low turnover and the aggregate displays increased turnover in mitotic cells. Aggregates are cleared during cell division. (A) ...

Day 1 - Band-Region chose to bat.

"Only these features allowed us to recapitulate the native structure of mitotic chromosomes in our model and understand how they can be segregated during cell division." In the future, the ...

For chromosomes to form the iconic X-shape that ensures the accurate passing of genetic information during cell division, a ...

For chromosomes to form the iconic X-shape that ensures the accurate passing of genetic information during cell division, a ...

Every time a cell divides to produce two new daughter cells., the genome must be replicated and evenly divided between those ...