Scientists have developed human stem cell models containing the notochord, a critical tissue that guides spine and nervous system formation during embryonic development. Using precise chemical signals ...

A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse—a mouse with two male parents—that lived until adulthood. Their results ...

The PCR product was then inserted into the pEGFP-N1 vector to construct the Cr-Nas15 (3 kb) > GFP fusion construct. The Ciona notochord specific expressed vector was constructed via replacing the CMV ...

The primary cilium is a paradigmatic organelle for studying compartmentalized cellular signaling in morphogenesis and disease (Anvarian et al., 2019; Nachury and Mick, 2019). The primary cilium is a ...

The notochord is a characteristic midline organ in chordate embryos that supports the ... Compared with the anatomically complex of vertebrate, Ciona embryonic tail is structurally simple, providing ...

Embryonic stem cell cultures are thought to self-organize into embryoid bodies, able to undergo symmetry-breaking, germ layer specification and even morphogenesis. Yet, it is unclear how to reconcile ...