Ferroptosis was determined by MDA levels, SOD levels, mitochondrial iron accumulation and ROS production. Ferroptosis-related proteins Slc7a11, Nrf2 and Gpx4 levels were measured by western blot, ...

This study aimed to investigate the pharmacological activity and underlying MOA. Conclusion: ORes inhibits breast cancer cell growth by inducing ferroptosis through suppression of the ...

We further treated the cells with CHIR99021, an activator of the Wnt signaling pathway. The results showed that CHIR99021 activated the GSK3β/β-catenin signaling pathway and reversed the PFOA-induced ...

Sulforaphane is a sulfur-rich compound found in certain species of the Brassica vegetable family. It's found in broccoli and other cruciferous vegetables, like bok choy, kale, and cabbage.