The first four disorders seem to result from defects in the excision repair pathway. In view of their ... pigmentosum complementing protein B; NER, nucleotide excision repair; pol η, polymerase ...

These included nucleotide metabolism pathways (e.g., thymine catabolism, thymidine de novo biosynthesis, and homocysteine metabolism), DNA repair pathways (e.g., nucleotide excision repair and ...

Will Kirk, best known for his role on The Repair Shop, has shared details of his big move to Surrey and how it has positively impacted his family life. The furniture restorer, 39, appeared on Alan ...

A growing movement is looking to change that. Right-to-repair advocates want to make items in our homes easier to fix and thus less prone to wind up in a landfill. For many, it’s a matter of ...

Presenters think they’re integral to a show, but are they? On the evidence of The Repair Shop (BBC One): nope. This 14th series is going ahead without Jay Blades, who was charged last year with ...

Scientists achieve a new understanding of the nucleotide excision repair process Sep 27, 2022 New approach uses oxidative photocatalysis on membranes to trigger cell death in cancer cells ...

"We found that the manner in which tumor cells die after radiotherapy depends on the engagement of specific DNA repair pathways, particularly when radiation is given at very high, focused doses.

State Key Laboratory of Antiviral Drugs, Pingyuan Laboratory, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, School of Chemistry and Chemical Engineering, Henan Normal University, ...

Five of the conditions (xeroderma pigmentosum, Cockayne's syndrome, trichothiodystrophy, Down syndrome, and triple-A syndrome) display a defect in the nucleotide excision repair pathway ...

CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair Discovering molecular pathways that sensitize cells to poly(ADP ...

Studies of polymorphisms of genetic pathways with strong prior hypotheses ... direct reversal of damage, mismatch repair, nucleotide excision repair, homologous recombination, non-homologous ...