Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

综合研究结论和讨论部分，这项研究首次全面地揭示了 WSSV 感染对虾后，葡萄糖和谷氨酰胺代谢重编程促进核苷酸从头合成的详细机制。不仅明确了谷氨酰胺在支持病毒复制方面的关键作用，还发现 Ras - PI3K - Akt - mTOR 通路并非是调控这一过程的唯一机制。这一成果为深入理解 WSSV 的致病机制提供了全新视角，也为开发针对 WSSV ...

DNA Synthesis Market, valued at a remarkable USD 2.89 billion in 2022, is set to embark on an unprecedented growth trajectory, projecting a robust Compound Annual Growth Rate (CAGR) of more than 19.63 ...

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in ...

The replication machinery does a good job of copying the nucleotide sequences until it gets to the telomeres ... The cell uses a process called fill-in synthesis to complete the shorter strand. But if ...

Oligonucleotide Synthesis Market Size & Growth Analysis: According to a new report by SNS Insider, the global Oligonucleotide Synthesis Market was valued at USD 3.72 billion in 2023 and is projected ...

This dual challenge - creating an efficient system to quickly locate information while ensuring its accuracy - mirrors what Lawrence Livermore National Laboratory (LLNL) researchers faced when working ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Total synthesis has long been a proving ground for advancing chemical thought, pushing ...

Nucleotide databases like NCBI nt have a broad range of applications, from diagnosing infection and tracking disease to monitoring environmental health, studying microbiomes and developing ...

Folic acid is a key player in one-carbon (1C) metabolism, which supports vital processes such as DNA repair, nucleotide synthesis, and lipid metabolism. It also contributes to the generation of ...

Metabolic pathways for serine synthesis, acquisition, and utilization in tumors and tumor-associated cells ... Serine is the primary source for synthesizing one-carbon (1C) units, linking amino acid ...