资讯

T cells are a type of white blood cell that is central to your immune defense. Four types that serve different functions include: CD4 and CD8 are two different types of glycoprotein found on the ...
5 Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore 6 Department of Diagnostic Radiology, Singapore General Hospital, Singapore 7 Department of Nuclear ...
CD4⁺和 CD8⁺调节性 T 细胞(Treg)在免疫调节中发挥关键作用,但二者存在诸多差异。 CD4⁺ Treg 表达转录因子 FOXP3,维持其抑制功能;CD8⁺ Treg 在人类中表达杀伤细胞免疫球蛋白样受体(KIRs),部分还表达颗粒酶 B(GZMB) ,在免疫调控中起重要作用。在人 ...
在免疫系统中,CD4⁺和CD8⁺调节性T细胞(Treg)扮演着至关重要的角色,二者在功能上却存在显著差异。首先,从细胞表型来看,这两个细胞群体的标志物不同。CD4⁺Treg通过表达转录因子FOXP3来维持其抑制性功能,而CD8⁺Treg则在人类中表达杀伤细胞免疫球蛋白样 ...
Patients with low hepatitis B core-related antigen (HBcrAg) level showed higher HBV-specific CD4 + T cell responses (independent of age), especially in HBV core-specific and HBV pol-specific T cell ...
研究样本来自健康供体的外周血单个核细胞(PBMC)。 研究结论表明,MTBVAC 在与 PBMC 相互作用的第一周就能激发有效的早期免疫反应,激活包括 CD4 和 γδ T 细胞在内的效应淋巴细胞群体,这些细胞的表型与能够控制分枝杆菌感染的个体中观察到的一致,同时还 ...
They analyzed 82 formalin-fixed, paraffin-embedded bladder CIS samples from BCG-treated patients. Responders and non-responders were classified based on relapse. Tissue sections were immunostained for ...
研究结果表明,低剂量 IL-2 在糖尿病和 OIR 小鼠模型中展现出了积极的治疗效果。 在 Tregs 和 CD8 + T 细胞方面,低剂量 IL-2 显著增加了血液和脾脏中 CD4 + CD25 + Foxp3 + Tregs 的数量,增强了 Tregs 的功能,提高了细胞毒性 T 淋巴细胞相关蛋白 4(CTLA4)、程序性细胞死亡 ...
IPEX PBMC were isolated from venous blood for the molecular diagnosis of IPEX syndrome by sequence analysis and flow cytometry after consent of the patients. For staining with Foxp3-specific rabbit ...