The Pancreas Section, led by Dr. Ferga Gleeson MD, is dedicated to publishing a broad spectrum of original clinical and scientific articles in various formats focused on advancing our current ...

Fibroblast populations are dynamic across morphogenic phases. Specialized fibroblasts appear to emerge from CD34 high mesenchymal progenitor cells, accompanied by increased Hedgehog signaling.

Mar. 13, 2025 — A study shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States ...

Apr. 10, 2025 — Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating ...

Type 1 diabetes (T1D) is an autoimmune condition, which means your immune system mistakenly attacks and destroys the beta cells in your pancreas that produce insulin. This cannot be reversed.

Treatments for T2D, including metformin, may temporarily manage blood sugar levels and other diabetes symptoms until the pancreas stops making insulin. This is often the point at which many who ...

Gut microbes can regulate the exocrine and endocrine functions of the pancreas and hormone production of the gastrointestinal tract, findings that may help develop potential treatments for diabetes ...

These findings motivated the study team to expand the research to human patients. Although the study included a small number of cases, the results indicate a potential new treatment for HGGs, ...

Ko et al. further demonstrated the effects of sunitinib on the subsets of MDSCs. [96] They first reported that administration of sunitinib to patients with RCC resulted in a significant reduction ...