This fundamental article significantly advances our understanding of FGF signalling, and in particular, highlights the complex modifications affecting this pathway. The evidence for the authors' ...

Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia ...

This heightened phosphatase function dephosphorylates the insulin receptor on critical tyrosine residues ... 205 in PTP1B as the principal site phosphorylated by PKA. Mutating this site blocked ...

Semi-phosphorylated IKK purified from Sf9 cells, exhibits the capacity for further autophosphorylation. Anti-phosphotyrosine immunoblotting indicated unexpected tyrosine phosphorylation. Contaminating ...