An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.

The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...

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DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine ...

By studying biomarkers known to be involved in gastrointestinal cancers, researchers have developed a biomarker algorithm that, when combined with a noninvasive method to collect esophageal cells for ...

They identified 30 candidate biomarkers for further study. Subsequent laboratory testing using methylation-based polymerase chain reaction selected 12 of these biomarkers as demonstrating ...

They identified 30 candidate biomarkers for further study. Subsequent laboratory testing using methylation-based polymerase ...

Dr. Aaron Wenger tells us about SPRQ chemistry, highlighting its unique benefits and role in expanding our understanding of rare diseases.

Epigenetic changes, encompassing DNA methylation, are involved in the occurrence and progression of tumors and hold promise as effective tools for screening, early diagnosis, treatment strategy, ...

The Signatera genome assay benefits from Natera’s patented multiplex polymerase chain reaction ... which is the result of growing expertise in methylation-based technologies and dovetails ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...