In animal models, inhibition of neutrophil chemokines or disruption of these chemokine gradients in the lung attenuates ALI. Molecules associated with enhanced wound closure, such as epithelial ...

Individuals with asthma and chronic obstructive pulmonary disease (COPD) were more vulnerable than healthy controls to ...

Firstly, we found that ATG suppressed PQ-induced pulmonary fibrosis by blocking the epithelial-mesenchymal transition (EMT). ATG reduced the expressions of Vimentin and α-SMA (lung fibrosis markers) ...

We studied its role in airway epithelial barrier integrity and cigarette smoke-induced epithelial responses. Materials and Methods: Protein level and localization of FAM13A was assessed with ...

A better understanding of inflammation and lung immunity over the past two decades has led to new, innovative treatments for ...

umcg.nl Background WNT signalling is activated during lung tissue damage and inflammation. We investigated whether lung epithelial expression of WNT ligands, receptors (frizzled; FZD) or target genes ...

A discovery offers new hope in the battle against pulmonary fibrosis, a debilitating lung condition that progressively makes it harder for patients to breathe. Scientists have pinpointed proteins in ...

Airway Reopening,Surface Tension,Pulmonary Epithelial Cells,Shear Stress,Air-liquid Interface,Boundary Element Method,Cells In Region,Channel Walls,Computational Investigation,Dynamic Surface ...

A discovery at Duke-NUS Medical School offers new hope in the battle against pulmonary fibrosis, a debilitating lung ...

An inhalable medicine with the potential to improve lung disease in people with cystic fibrosis, irrespective of their mutation type.