This paper discussed the role of AlkB homologue 5 (Alkbh5) in the progression of lipopolysaccharide (LPS)-induced acute lung injury (ALI). LPS-induced ALI models were established in Alkbh5 knockout ...

Study Links Intense Energy Bursts to Ventilator-Induced Lung Injury Mar. 3, 2025 — A new study sheds light on ventilator-induced lung injury, a complication that gained increased attention ...

1 Department of Thoracic Surgery, Affiliated Hospital of Qingdao University, Qingdao, Shandong, China 2 Department of Thoracic Surgery, Peking University People’s Hospital, Beijing, Beijing, China ...

College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention ...

zju.edu.cn Background Type 2 immune dysfunction contributes to acute lung injury and lethality following haemorrhagic shock (HS) and trauma. Group 2 innate lymphoid cells (ILC2s) play a significant ...

It is characterized by the deterioration of cartilage and the extracellular matrix (ECM), synovial inflammation, and subchondral bone remodeling. Recent studies have highlighted pyroptosis—a form of ...

The significance of this manuscript is the finding that trained immunity is actually a two-edged sword, herein, detrimental in the context of LPS-induced Acute Lung Injury that is mediated by AMs.

We furthermore demonstrate that AM reprogramming at both the transcriptional and metabolic levels exacerbate lung injury following bacterial (LPS) or viral (polyI:C) challenges via a neutrophil/IFN-γ ...

Got an aching back? Experts say it’s worth bringing up to your doctor. (Getty Images) ...