Active caspase 1 causes pyroptosis and is responsible ... stimulate adaptive immune responses and enhance host survival; however, inappropriate activation of caspase 1 can lead to pathological ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Researchers discovered that EBV infection triggers macrophage pyroptosis—a form of inflammatory ... metabolic dysregulation, and immune activation in UC. Dr. Hu Zhang, the study's corresponding ...

Neutrophils play a crucial role in the immune response, acting as the most abundant white blood cells responsible for frontline defense against infections ...

Autophagy is related to host anti-virus tolerable TH3 immunity. Pyroptosis is related to host anti-intracellular micro-organism eradicable TH1 immunity. Ferroptosis is related to host anti ...

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the ...

In a study published today (October 20) in Science Translational Medicine, researchers show that these cells, the most abundant in circulation, also alert the immune system to the presence of bacteria ...

Researchers discovered that EBV infection triggers macrophage pyroptosis—a form of inflammatory ... metabolic dysregulation, and immune activation in UC. Dr. Hu Zhang, the study's corresponding ...