(A-B) Knockdown of SLC7A11 (A) and GPX4 (B) induced increased lipid peroxidation (BODIPY-C11) in JIMT1. (C-D) Treatment with erastin, RSL3 and cysteine starvation for 12 hours induced lipid ...

The following is a summary of “Expression and prognostic value of ferritinophagy-related NCOA4 gene in low-grade glioma: integration of bioinformatics and experimental validation,” published in the ...

Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi 712100, People’s Republic of China ...

Additionally, the concomitant phenomenon of ferritinophagy, the autophagic degradation of ferritin, assumes a pivotal role by facilitating the liberation of iron ions from ferritin, thereby advancing ...

Here, we showed that ferroptosis inducer RSL3 initiated cell death and ROS accumulation in HCT116, LoVo, and HT29 CRC cells over a 24 h time course. Furthermore, we found that ROS levels and ...