Get Instant Summarized Text (Gist) Specific protein regions within the estrogen receptor, crucial for breast cancer development, have been identified as 'molecular switches' that coordinate ...

Eli Lilly and Company (NYSE: LLY) today announced results from the Phase 3 EMBER-3 study of imlunestrant, an investigational, oral selective estrogen receptor degrader (SERD), in patients with ...

A separate retrospective analysis of a larger cohort of 1091 patients with advanced NSCLC who were progression-free after at least 2 years of immune checkpoint inhibitor therapy similarly did not find ...

The drugs cited are known as selective estrogen receptor modulators, or SERMs, which “were often marketed and sold for body-building purposes to reduce male breast enlargement (gynecomastia), a ...

Metronomic capecitabine combined with an aromatase inhibitor extends median progression-free survival to 20.9 months compared with 11.9 months for aromatase inhibitor alone in hormone receptor ...

Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China ...

Transneural Therapeutics Inc. has described 5-HT2A receptor modulators reported to be useful for the treatment of depression, anxiety, substance abuse and dependence, and headache.

This is a new kind of oral selective estrogen receptor degrader (SERD), used to treat estrogen receptor-positive (ER+ ... surgical), who have progressed on or after previous endocrine therapies, such ...

As our knowledge about aromatase inhibitors and their side effects has expanded, questions remain unanswered with regards to their influence on cognition. Future study designs evaluating cognitive ...

Commonly prescribed medications for reducing estrogen levels include aromatase inhibitors (AIs) such as letrozole and anastrozole, as well as selective estrogen receptor modulators (SERMs ...

Some common estrogen blockers used by bodybuilders include aromatase inhibitors, such as anastrozole and letrozole, as well as selective estrogen receptor modulators (SERMs), such as tamoxifen.