A Vanderbilt University patent discloses new muscarinic M4 receptor positive allosteric modulators and agonists reported to be useful for the treatment of Alzheimer’s disease, pain, schizophrenia, ...

But his Kalispell, Montana-based business Rat’s Army marketed and sold a variety of products, including selective estrogen receptor modulators (SERMs), which can block estrogen in some applications.

A more effective treatment for aggressive breast cancer: Two inhibitor drugs show potential 13 hours ago CAR-T cells can arm bystander T cells with CAR molecules in tumor microenvironment ...

Eli Lilly and Company (NYSE: LLY) today announced results from the Phase 3 EMBER-3 study of imlunestrant, an investigational, oral selective estrogen receptor degrader (SERD), in patients with ...

Tyrosine (Tyr) phosphorylation of p27 by Abl and Src family kinases reduces p27–CDK2 inhibition and transforms p27 from inhibitor to substrate of cyclin–CDK2 complexes. p27 phosphorylation at ...

Jiangsu Key Laboratory of Drug Design and Optimization and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China Jiangsu Key Laboratory of Drug Design and ...

The drugs cited are known as selective estrogen receptor modulators, or SERMs, which “were often marketed and sold for body-building purposes to reduce male breast enlargement (gynecomastia), a ...