Scientists at Dongguk University and Korean Research Institute of Bioscience and Biotechnology have disclosed benzofuran compounds targeting heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2B1) ...

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review ...

2017年7月5日，南京医科大学附属淮安第一人民医院神经外科在Oncology Research（中科院四区 IF=2）期刊上在线发表题为 "Overexpression of Protease Serine 8 Inhibits Glioma ...

An Osaka Metropolitan University-led Egypt-Japan research team found E. coli prevalent in over 25% of popular milk and dairy products in Egypt.

Recombinase efficiency increases allow Qi Biodesign to insert 20-30 kb (5 or 6 genes) at one time at one location across a variety of different crop genetics. In addition, a large team at Qi Biodesign ...

2025 年 2 月 13 日，诺奖得主、华盛顿大学 David Baker 团队在 Science 上发表了题为“Computational design of serine hydrolases” 的论文，文章展示了在酶设计领域的新突破。 该研究利用 AI 首次实现了从头设计丝氨酸水解酶，完成了对复杂活性位点的精准构建和多步催化循环的结构兼容性评估。

The company discovered Serine Protease Inhibitors, a class of proteins, which quell inflammation, and Lauder will be ...

Terremoto Biosciences Inc. has synthesized new 3H-imidazo[4,5-b]pyridine compounds acting as RAC-α serine/threonine-protein kinase (AKT1; PKB-α) inhibitors reported to be useful for the treatment of ...

A team from the University of Washington led by Nobel laureate David Baker is using artificial intelligence to design effective enzymes from scratch — an accomplishment the researchers call "one of ...

In the case of PSKH1, which is a ‘signalling molecule’, the researchers found that when it binds to a protein called ‘Calmodulin’ PSKH1 is “switched on” and when it binds to a protein called ...