By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent continuous stimulation of postsynaptic neurons. There are two types of removal: Re-uptake – the ...

Serafini and colleagues provide evidence that neuroligin acts as a trans-neuronal signal to induce presynaptic differentiation at neuron–neuron connections in vitro. To form a synaptic ...

Similarly, we have an intuitive idea of the factors that affect synaptic efficacy. So, if release probability or the number of quanta increases at a given synapse, its efficacy will also increase.