Peroxidases or peroxide reductases (EC number 1.11.1.x) are a large group of enzymes which play a role in various biological processes. They are named after the fact that they commonly break up peroxides, and should not be confused with other enzymes that produce peroxide, which are often oxidases.

Peroxidases represent a family of isoenzymes actively involved in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis and pathogenesis of several diseases. Different types of peroxidases have organ, tissues, cellular and …

This peroxidase activity is essential for metabolism, protection against oxidative stress, and regulating redox signaling processes within human cells. Due to the multifaceted role of Prxs in numerous cellular contexts, studying Prxs’ function in health and disease is of high relevance.

Peroxidase is an enzyme in the group of oxidoreductases that is widely distributed in nature. It can catalyze the oxidation of various organic and inorganic substrates by reacting with hydrogen peroxide and similar molecules. Due to its wide catalytic activity, peroxidases can …

Myeloperoxidase (MPO) is an enzyme with remarkable diversity in health and disease. MPO levels usually correlate with disease severity and is a key biomarker. MPO has roles in COVID-19, drug oxidation, & neutrophil extracellular traps. Clinical MPO inhibitors require further study to elucidate protective activity. 1.

Peroxidases are enzymes that primarily function to oxidize hydrogen donors using peroxides. They have a high specificity for hydrogen peroxide and can accept a wide range of hydrogen donors, including polyphenols. These enzymes are glycoproteins with a hematin compound as a cofactor and have molecular weights ranging from 30 to 55 kDa.

2021年5月1日 · Peroxidase is an enzyme in the group of oxidoreductases that is widely distributed in nature. It can catalyze the oxidation of various organic and inorganic substrates by reacting with hydrogen peroxide and similar molecules.

2011年1月13日 · Peroxidases are oxidoreductases produced by a number of microorganisms and plants. Peroxidases catalyse a variety of reactions in the presence of peroxides such as hydrogen peroxide.

By now, enzymes termed peroxidases represent a heterogeneous group of distinct enzyme families that operate by different catalytic principles and fulfill diverse biological functions, detoxifying H2O2 being just one of many aspects.

2021年7月23日 · For catalase and peroxidase, the evidence indicates that hydrogen peroxide binds to the ferric center and then undergoes heterolysis at the O—O bond. Heterolytic cleavage requires a significant separation of positive and negative charge in the transition state.